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COMPREHENSIVE ANALYSIS OF ANTIBACTERIA SOAPS

CHAPTER ONE

INTRODUCTION

In the first known comprehensive analysis, antibacterial soaps work in terms of killing/inhibiting micro-organisms than plain soaps because of the way the main active ingredient (triclosan) in many bacterial soaps reacts in the cells (Furuya, 2006). The soaps containing triclosan used in the community setting are more effective than plain soap at preventing infections, illness symptoms, as well as reducing bacteria (Harbarth, 2005).

Anti-bacterial soaps that contain triclosan is used in higher concentrations in hospitals and other clinical settings, they are also more effective at reducing bacteria and other micro-organisms (Lowy, 2006).

MECHANISM OF ACTION

At in-use concentrations, triclosan acts as a biocide, with multiple cytoplasmic and membrane targets. At lower concentrations, however, triclosan appears bacteriostatic and is seen to target bacteria mainly by inhibiting fatty acid synthesis.

Some bacterial species can develop low-level resistance to triclosan at its lower bacteriostatic concentrations (Snow, 1999). These antibacterial soaps; triclosan and glycerin can also be used in inhibiting bacterial infections such as staphylococcus aureus, Escherichia coli, candida albicans (Rubin J.R., 1999).

GYCERIN

Glycerin the world famous antiseptic product, was one of the first soaps available, that would actually kill bacteria was developed in the 19th century by Edward cook company of London. Glycerin became known for not only its antibacterial symptoms of prickly heat and other irritating skin problems but also refreshing your body and keeping you healthy (zhu, 2010). This soap is used in washing, sterilizing and removing the body odour, it is also used in cleaning the skin and mucous membrane (zhu, 2010).


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